Outlander Colum MacKenzies condition explained and how | UK News

Outlander devotees have been left in a state of longing during the Droughtlander, with no new episodes of the Starz sequence in sight. However, many have been revisiting the show, sparking curiosity within the character of Colum McKenzie (portrayed by Gary Lewis), the uncle of Jamie Fraser (Sam Heughan).

Colum made his debut in Outlander’s first season when Claire Fraser (Caitríona Balfe) discovered herself at Castle Leoch and found more in regards to the enigmatic males who had saved her from Captain ‘Black Jack’ Randall (Tobias Menzies). The character was the clan chieftain or Laird of the MacKenzie Clan however closely relied on his youthful brother Dougal MacKenzie (Graham McTavish).

It was revealed that Colum suffered from a painful and degenerative condition often known as Toulouse-Lautrec Syndrome or Pycnodysostosis/PKND/PYCD, which hindered his capacity to stroll. Metabolic Support UK explains that Pycnodysostosis is a condition brought on by gene mutations, resulting in an enzyme that breaks down substances like bone proteins and sorts of collagen within the physique.

Typically, these substances are reabsorbed back into the physique, however these with this condition is not going to utterly break down these supplies. Over time, they accumulate within the physique and grow to be poisonous, affecting each cells and tissues.

The charity additional states that the condition is extremely uncommon and varies from affected person to affected person, experiences the Scottish Daily Express.

Common signs of Pycnodysostosis embrace a shorter stature, a high brow, irregular pelvis bone and an irregular collarbone, amongst different issues. It’s an inherited condition, however carriers of the gene haven’t got it as a result of their different genes are working usually.

Therefore, Colum is prone to have inherited the gene from his mother and father in the event that they carried the gene, regardless that they did not have the condition. There have been initial doubts over whether or not Colum ought to lead the clan given his condition, nonetheless, he was chosen over Dougal to be the Laird.

This is a storyline prone to unfold within the prequel sequence Outlander: Blood of My Blood, set to air later this 12 months. Despite the ache in his legs, Colum used wine for reduction and even strutted across the fortress as a show of energy.

In Outlander, Claire euthanised Colum after the ache turned insufferable for him earlier than the Battle of Culloden. He had grow to be sick and the ache was an excessive amount of to bear with Claire helping him together with her medical information.

Esteemed actor, Lewis, 66, portrayed Colum throughout seasons one and two of Outlander earlier than his character met his tragic finish. Lewis was already well-known earlier than his function in Outlander, maybe most notably as enjoying the miner father to Jamie Bell’s titular Billy Elliot.

He additionally had roles in Gangs of New York and Eragon, and Joyeux Noël. Since leaving Outlander he is starred in His Dark Materials, The Bay, The Level, One of Us and Frontier.

Most lately, he is graced the screens in Franklin, Vigil, Granite Harbour and Disney+’s A Thousand Blows, portraying the character Jack Mac. As per IMDb, his upcoming tasks embrace North Pole: 90° North, I Feel Fine and The Undertow.

Outlander season 7 is on the market to buy now on Digital and is streaming on MGM+ now through Prime Video